Accuracy of Serologic Tests and HLA-DQ Typing for Diagnosing Celiac Disease

  title={Accuracy of Serologic Tests and HLA-DQ Typing for Diagnosing Celiac Disease},
  author={M. Hadithi and B. V. von Blomberg and J. B. Crusius and E. Bloemena and P. Kostense and J. Meijer and C. Mulder and C. Stehouwer and Amado Pea},
  journal={Annals of Internal Medicine},
  • M. Hadithi, B. V. von Blomberg, +6 authors Amado Pea
  • Published 2007
  • Medicine
  • Annals of Internal Medicine
  • Context The value of adding HLA genetic typing to serologic testing for celiac disease is not well defined. Contribution In this prospective study of patients referred for evaluation of celiac disease, the test performance of combinations of genetic typing and serologic testing was similar to that of either strategy alone. Caution The small number of cases of celiac disease precluded meaningful comparisons of testing strategies. Implications The combination of genetic typing and serologic… CONTINUE READING
    154 Citations
    Tailored Testing for Celiac Disease
    • 31
    • PDF
    Utility of testing patients, on presentation, for serologic features of celiac disease.
    • 7
    Contemporary celiac disease diagnosis: is a biopsy avoidable?
    • 15
    Testing for gluten-related disorders in clinical practice: the role of serology in managing the spectrum of gluten sensitivity.
    • 36
    • PDF
    Clinical Utility of Celiac Disease-Associated HLA Testing
    • 26
    The potential usefulness of human leukocyte antigen typing for celiac disease screening: A systematic review and meta-analysis.
    • 8
    • PDF
    A novel serogenetic approach determines the community prevalence of celiac disease and informs improved diagnostic pathways
    • 86
    • PDF
    Serological testing for celiac disease in adults
    • 24
    Overview of biomarkers for diagnosis and monitoring of celiac disease.
    • I. Brusca
    • Medicine
    • Advances in clinical chemistry
    • 2015
    • 35


    HLA-DQ typing in the diagnosis of celiac disease
    • 167
    The diagnostic accuracy of serologic tests for celiac disease: a systematic review.
    • 489
    Diagnostic criteria for coeliac disease: time for change?
    • 43
    Diagnostic accuracy of coeliac serological tests: a prospective study
    • 97
    Accuracy and cost-effectiveness of a new strategy to screen for celiac disease in children with Down syndrome.
    • 95
    New diagnostic findings in coeliac disease.
    • 33
    Autoantibodies to tissue transglutaminase as predictors of celiac disease.
    • 586
    Reliance on serum endomysial antibody testing underestimates the true prevalence of coeliac disease by one fifth.
    • 150