Accuracy of MicroRNA Discovery Pipelines in Non-Model Organisms Using Closely Related Species Genomes

@inproceedings{Etebari2014AccuracyOM,
  title={Accuracy of MicroRNA Discovery Pipelines in Non-Model Organisms Using Closely Related Species Genomes},
  author={Kayvan Etebari and Sassan Asgari},
  booktitle={PloS one},
  year={2014}
}
Mapping small reads to genome reference is an essential and more common approach to identify microRNAs (miRNAs) in an organism. Using closely related species genomes as proxy references can facilitate miRNA expression studies in non-model species that their genomes are not available. However, the level of error this introduces is mostly unknown, as this is the result of evolutionary distance between the proxy reference and the species of interest. To evaluate the accuracy of miRNA discovery… CONTINUE READING
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