Accumulation of the hydroxyl free radical markers meta-, ortho-tyrosine and DOPA in cataractous lenses is accompanied by a lower protein and phenylalanine content of the water-soluble phase

@article{Molnr2005AccumulationOT,
  title={Accumulation of the hydroxyl free radical markers meta-, ortho-tyrosine and DOPA in cataractous lenses is accompanied by a lower protein and phenylalanine content of the water-soluble phase},
  author={Gergő Attila Moln{\'a}r and Vanda Nemes and Zsolt Bir{\'o} and Andrea Lud{\'a}ny and Zolt{\'a}n Wagner and Istv{\'a}n Wittmann},
  journal={Free Radical Research},
  year={2005},
  volume={39},
  pages={1359 - 1366}
}
Post-translational modifications of lens proteins play a crucial role in the formation of cataract during ageing. The aim of our study was to analyze protein composition of the cataractous lenses by electrophoretic and high-performance liquid chromatographic (HPLC) methods. Samples were obtained after extracapsular cataract surgery performed by phacoemulsification technique from cataract patients with type 2 diabetes mellitus (DM CAT, n = 22) and cataract patients without diabetes (non-DM CAT… 
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