Accumulation of norepinephrine (NE) by rat organs in vivo.


In anesthetized rats intravenously infused, norepinephrine (NE) was accumulated by the heart, the spleen and the lung in a dose-related manner. With the lower dose of NE (2.5 mg/kg) the organ/blood ratios were more than unity and were generally greater than with higher doses (5 and 10 mg/kg), indicating that accumulation occurred by active uptake. Nialamide… (More)


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@article{Sivaramakrishna1975AccumulationON, title={Accumulation of norepinephrine (NE) by rat organs in vivo.}, author={N Sivaramakrishna and Om Datt Gulati}, journal={Pharmacology}, year={1975}, volume={13 4}, pages={365-77} }