Accumulation of nitrite and sulfite in yeast cells and synergistic depletion of the intracellular ATP content.

@article{Hinze1985AccumulationON,
  title={Accumulation of nitrite and sulfite in yeast cells and synergistic depletion of the intracellular ATP content.},
  author={Helga Hinze and Helmut Holzer},
  journal={Zeitschrift fur Lebensmittel-Untersuchung und -Forschung},
  year={1985},
  volume={180 2},
  pages={117-20}
}
When nitrite or sulfite are applied to yeast cells below pH 5.0, an enormous intracellular accumulation occurs. It is assumed that nitrite and sulfite penetrate the cell membrane in their undissociated forms as nitrous acid (pK = 3.3) or sulfurous acid (pK = 1.8), respectively. Due to the neutral intracellular pH they are trapped inside the cell in their… CONTINUE READING