Accumulation of natural and synthetic betaines by a mammalian renal cell line.

@article{Randall1996AccumulationON,
  title={Accumulation of natural and synthetic betaines by a mammalian renal cell line.},
  author={K. Randall and M. Lever and B. Peddie and S. Chambers},
  journal={Biochemistry and cell biology = Biochimie et biologie cellulaire},
  year={1996},
  volume={74 2},
  pages={
          283-7
        }
}
  • K. Randall, M. Lever, +1 author S. Chambers
  • Published 1996
  • Chemistry, Medicine
  • Biochemistry and cell biology = Biochimie et biologie cellulaire
  • Intracellular accumulation of different betaines was compared in osmotically stressed Madin Darby canine kidney (MDCK) cells to model the betaine accumulation specificity of the mammalian inner medulla and to show how this accumulation differed from that of bacteria. All betaines accumulated less than glycine betaine. Arsenobetaine (the arsenic analogue of glycine betaine) accumulated to 12% of the glycine betaine levels and the sulphur analogue dimethylthetin accumulated to >80%. Most… CONTINUE READING
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    References

    SHOWING 1-10 OF 26 REFERENCES
    Osmoregulation of betaine transport in mammalian renal medullary cells.
    • 83
    Competitive accumulation of betaines by Escherichia coli K-12 and derivative strains lacking betaine porters.
    • 31
    Cloning of a Na(+)- and Cl(-)-dependent betaine transporter that is regulated by hypertonicity.
    • 346
    Relationship between osmoprotection and the structure and intracellular accumulation of betaines by Escherichia coli.
    • 46
    • PDF
    Structure-activity relationship of glycine betaine analogs on osmotolerance of enteric bacteria.
    • 15
    Dimethylthetin can substitute for glycine betaine as an osmoprotectant molecule for Escherichia coli.
    • 118
    • PDF
    Survey of osmolytes in renal cell lines.
    • 101
    Glycine betaine and proline betaine in human blood and urine.
    • 93
    Predominant osmotically active organic solutes in rat and rabbit renal medullas.
    • 357
    • PDF