Accumulation of inorganic polyphosphate in phoU mutants of Escherichia coli and Synechocystis sp. strain PCC6803.

@article{Morohoshi2002AccumulationOI,
  title={Accumulation of inorganic polyphosphate in phoU mutants of Escherichia coli and Synechocystis sp. strain PCC6803.},
  author={Tomohiro Morohoshi and Tatsuya Maruo and Yoko Shirai and Junichi Kato and Tsukasa Ikeda and Noboru Takiguchi and Hisao Ohtake and Akio Kuroda},
  journal={Applied and environmental microbiology},
  year={2002},
  volume={68 8},
  pages={4107-10}
}
The biological process for phosphate (P(i)) removal is based on the use of bacteria capable of accumulating inorganic polyphosphate (polyP). We obtained Escherichia coli mutants which accumulate a large amount of polyP. The polyP accumulation in these mutants was ascribed to a mutation of the phoU gene that encodes a negative regulator of the P(i) regulon. Insertional inactivation of the phoU gene also elevated the intracellular level of polyP in Synechocystis sp. strain PCC6803. The mutant… CONTINUE READING
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