Accumulation of effector memory CD8+ T cells in nasal polyps.

@article{Pant2013AccumulationOE,
  title={Accumulation of effector memory CD8+ T cells in nasal polyps.},
  author={Harshita Pant and Amy Hughes and Dijana Miljkovic and Mark A Schembri and Peter John Wormald and Peta C Macardle and Randall Grose and Heddy Zola and Doreen Krumbiegel},
  journal={American journal of rhinology & allergy},
  year={2013},
  volume={27 5},
  pages={
          e117-26
        }
}
BACKGROUND T lymphocytes are prevalent in sinus mucosa and are implicated in chronic rhinosinusitis (CRS) pathogenesis. However, the major T-cell subpopulations, helper (CD4+) and cytotoxic (CD8+), have not been adequately examined in CRS. This study was designed to characterize human sinus mucosa and peripheral blood (PB) CD4+ and CD8+ T cells and their level of differentiation in CRS with nasal polyps (NPs), CRS without NPs, and control patients. METHODS A prospective study was performed… CONTINUE READING
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