Accumulation of dsRNA in endosomes contributes to inefficient RNA interference in the fall armyworm, Spodoptera frugiperda.

@article{Yoon2017AccumulationOD,
  title={Accumulation of dsRNA in endosomes contributes to inefficient RNA interference in the fall armyworm, Spodoptera frugiperda.},
  author={June-Sun Yoon and Dhandapani Gurusamy and Subba Reddy Palli},
  journal={Insect biochemistry and molecular biology},
  year={2017},
  volume={90},
  pages={53-60}
}
RNA interference (RNAi) efficiency varies among insects studied. The barriers for successful RNAi include the presence of double-stranded ribonucleases (dsRNase) in the lumen and hemolymph that could potentially digest double-stranded RNA (dsRNA) and the variability in the transport of dsRNA into and within the cells. We recently showed that the dsRNAs are… CONTINUE READING