Accumulation of (n−9)-eicosatrienoic and docosatrienoic acids in human fibroblast phospholipids


An essential fatty acid (EFA) deficiency-like profile of fatty acids has been observed in HF-1 human skin fibro-blasts cultured at clonal densities in MCDB 110 and 0.4% fetal bovine serum (FBS). The profile was characterized by an accumulation of 16∶1n−7, 18∶1n−9, 20∶3n−9 and 22∶3n−9, a reduction of n−6 fatty acids and a reduction in total polyunsaturated… (More)
DOI: 10.1007/BF02536211


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