Accumulation in liver and spleen of metal particles generated at nonbearing surfaces in hip arthroplasty.

@article{Urban2004AccumulationIL,
  title={Accumulation in liver and spleen of metal particles generated at nonbearing surfaces in hip arthroplasty.},
  author={Robert M. Urban and Michael J Tomlinson and Deborah J Hall and Joshua.J. Jacobs},
  journal={The Journal of arthroplasty},
  year={2004},
  volume={19 8 Suppl 3},
  pages={
          94-101
        }
}
Systemic migration of metal particles generated at nonbearing surfaces rather than the intended primary bearing was studied in postmortem specimens from 30 patients with total hip arthroplasty. Using light and electron microscopy with x-ray microanalysis, submicrometer metal particles were identified within macrophages in the liver and/or the spleen in 11 of 15 patients with a revised arthroplasty and in 2 of 15 patients with primary hip arthroplasty. The macrophages formed focal aggregates in… CONTINUE READING
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