Accumulation and salvage of adenosine and inosine by isolated mature cardiac myocytes.

Abstract

Reoxygenation of ischaemic, energy-depleted heart does not result in sufficiently rapid regeneration of normal adenine nucleotide concentrations for preservation of cardiac function and structure. Salvage of nucleoside as a mechanism for restoration of ATP in the post-ischaemic myocardium is limited by efflux of adenosine during ischaemia. Isolated cardiac… (More)

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@article{Bowditch1985AccumulationAS, title={Accumulation and salvage of adenosine and inosine by isolated mature cardiac myocytes.}, author={John Bowditch and A. K. Brown and Jessie Dow}, journal={Biochimica et biophysica acta}, year={1985}, volume={844 2}, pages={119-28} }