Accumulated basement membrane material in hyalinizing trabecular tumors of the thyroid.

@article{Katoh1999AccumulatedBM,
  title={Accumulated basement membrane material in hyalinizing trabecular tumors of the thyroid.},
  author={R. Katoh and Kenji Kakudo and Akira Kawaoi},
  journal={Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc},
  year={1999},
  volume={12 11},
  pages={1057-61}
}
We report here four additional cases of hyalinizing trabecular adenoma of the thyroid and describe the findings of the accumulated basement membrane (BM) material. Focal lumpy depositions of BM material were noted in the stroma of all four tumors and were particularly prominent in two. Antibodies against type IV collagen and laminin strongly immunoreacted with this material, which also showed diastase-resistant periodic acid-Schiff positivity. The ultrastructural findings of accumulated… CONTINUE READING