Acclimatization to hypoxia modulates the tryptophan 2,3-dioxygenase activity in rats exposed to simulated high altitude.

Abstract

1. Exposure of rats to an 8000 m altitude increased the hepatic tryptophan 2,3-dioxygenase (EC 1.13.1.12) activity. 2. Acclimatization to hypoxia by a repeated exposure to an altitude of 5000 m induced a marked decrease in liver tryptophan dioxygenase activity after the rats were subjected to an 8000 m altitude, but a pre-exposure to 4000 m altitude showed… (More)

Topics

Cite this paper

@article{Yoshino1991AcclimatizationTH, title={Acclimatization to hypoxia modulates the tryptophan 2,3-dioxygenase activity in rats exposed to simulated high altitude.}, author={Masataka Yoshino and Shigemi Mori and Masayuki Nakatsuka and Yasushi Shibata}, journal={Comparative biochemistry and physiology. B, Comparative biochemistry}, year={1991}, volume={99 3}, pages={571-3} }