Accidental overdose of intravenous ofloxacin with benign outcome.


A patient accidentally received approximately 3 g of ofloxacin intravenously. She experienced only moderately severe central nervous system symptoms, which resolved within 9 h. The peak serum ofloxacin level was 39.3 micrograms/ml, approximately seven times the usual peak level. Ofloxacin may possess a considerable safety margin in humans.

Cite this paper

@article{Kohler1991AccidentalOO, title={Accidental overdose of intravenous ofloxacin with benign outcome.}, author={Richard Kohler and Nancy Arkins and Kenneth J Tack}, journal={Antimicrobial agents and chemotherapy}, year={1991}, volume={35 6}, pages={1239-40} }