Accessories to the crime: recent advances in HIV accessory protein biology.

  title={Accessories to the crime: recent advances in HIV accessory protein biology.},
  author={Thomas Gramberg and Nicole R Sunseri and Nathaniel R. Landau},
  journal={Current HIV/AIDS reports},
  volume={6 1},
Recent advances in understanding the roles of the lentiviral accessory proteins have provided fascinating insight into the molecular biology of the virus and uncovered previously unappreciated innate immune mechanisms by which the host defends itself. HIV-1 and other lentiviruses have developed accessory proteins that counterattack the antiviral defenses in a sort of evolutionary battle. The virus is remarkably adept at co-opting cellular degradative pathways to destroy the protective proteins… CONTINUE READING

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