Accessing key steps of human tumor progression in vivo by using an avian embryo model.

  title={Accessing key steps of human tumor progression in vivo by using an avian embryo model.},
  author={Martin Hagedorn and Sophie Javerzat and Delphine Gilges and Aur{\'e}lie Meyre and Benjamin de Lafarge and A. R. Eichmann and Andr{\'e}as Bikfalvi},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={102 5},
Experimental in vivo tumor models are essential for comprehending the dynamic process of human cancer progression, identifying therapeutic targets, and evaluating antitumor drugs. However, current rodent models are limited by high costs, long experimental duration, variability, restricted accessibility to the tumor, and major ethical concerns. To avoid these shortcomings, we investigated whether tumor growth on the chick chorio-allantoic membrane after human glioblastoma cell grafting would… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 90 extracted citations

In vivo PET/CT in a human glioblastoma chicken chorioallantoic membrane model: a new tool for oncology and radiotracer development.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine • 2013
View 4 Excerpts
Highly Influenced

Amelioration of Dalton's lymphoma-induced angiogenesis by melatonin.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine • 2017


Publications referenced by this paper.

The Principles of Humane Experimental Technique (Universities Federation for Animal

W.M.S. Russell, R. L. Burch

Similar Papers

Loading similar papers…