Access to molecular guided therapy for Langerhans cell histiocytosis patients.


To the Editor: The patient described in our case report presented with intolerable skin discomfort related to a BRAF V600E positive, multi-refractory Langerhans cell histiocytosis (LCH), resulting in suicidal ideation. In our institution, the patient was eligible for an off-label vemurafenib treatment after multidisciplinary consultation and signed informed… (More)
DOI: 10.1016/j.jaad.2015.03.007