Acceleration of muscle regeneration by local injection of muscle-specific microRNAs in rat skeletal muscle injury model

@inproceedings{Nakasa2010AccelerationOM,
  title={Acceleration of muscle regeneration by local injection of muscle-specific microRNAs in rat skeletal muscle injury model},
  author={Tomoyuki Nakasa and Masakazu Ishikawa and Ming Shi and Hayatoshi Shibuya and Nobuo Adachi and Mitsuo Ochi},
  booktitle={Journal of cellular and molecular medicine},
  year={2010}
}
MicroRNA (miRNA)s are a class of non-coding RNAs that regulate gene expression post-transcriptionally. Muscle-specific miRNA, miRNA (miR)-1, miR-133 and miR-206 play a crucial role in the regulation of muscle development and homeostasis. Muscle injuries are a common musculoskeletal disorder, and the most effective treatment has not been established yet. The purpose of this study was to demonstrate that a local injection of double-stranded (ds) miR-1, miR-133 and 206 can accelerate muscle… CONTINUE READING

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