Accelerating progress in induced pluripotent stem cell research for neurological diseases.

@article{Ito2012AcceleratingPI,
  title={Accelerating progress in induced pluripotent stem cell research for neurological diseases.},
  author={Daisuke Ito and Hideyuki Okano and Norihiro Suzuki},
  journal={Annals of neurology},
  year={2012},
  volume={72 2},
  pages={167-74}
}
In 2006, Yamanaka's group pioneered a method for reprogramming somatic cells by introducing definite transcription factors, which enabled the generation of induced pluripotent stem cells (iPSCs) with pluripotency comparable to that of embryonic stem cells. These iPSCs are attracting considerable attention for their potential in rejection-tolerance personalized replacement therapy. In recent years, patient-derived iPSCs have been used to recapitulate the phenotypes of neurological diseases and… CONTINUE READING