Accelerating Discovery and Functional Analysis of Small RNAs with New Technologies.

@article{Barquist2015AcceleratingDA,
  title={Accelerating Discovery and Functional Analysis of Small RNAs with New Technologies.},
  author={Lars Barquist and J{\"o}rg Vogel},
  journal={Annual review of genetics},
  year={2015},
  volume={49},
  pages={367-94}
}
Over the past decade, bacterial small RNAs (sRNAs) have gone from a biological curiosity to being recognized as a major class of regulatory molecules. High-throughput methods for sampling the transcriptional output of bacterial cells demonstrate that sRNAs are universal features of bacterial transcriptomes, are plentiful, and appear to vary extensively over evolutionary time. With ever more bacteria coming under study, the question becomes how can we accelerate the discovery and functional… CONTINUE READING
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