Accelerated rejection of Nematospiroides dubius intestinal worms in mice sensitized with adult worms.

@article{Hurley1980AcceleratedRO,
  title={Accelerated rejection of Nematospiroides dubius intestinal worms in mice sensitized with adult worms.},
  author={James C Hurley and Karen Day and Graham F. Mitchell},
  journal={The Australian journal of experimental biology and medical science},
  year={1980},
  volume={58 3},
  pages={231-40}
}
After oral administration of infective third stage larvae (L3) of Nematospiroides dubius to young mice, intestinal worms persist for many weeks. However, in mice injected parenterally with N. dubius adult worms, the intraluminal intestinal infection arising after L3 administration can be terminated within 3 to 4 weeks. This accelerated rejection is seen in sensitized BALB/c mice (and (CBA/H X BALB/c)F1 mice) and in particular females, but has not been demonstrated in sensitized CBA/H mice. In… CONTINUE READING