Accelerated functional brain aging in major depressive disorder: evidence from a large scale fMRI analysis of Chinese participants

  title={Accelerated functional brain aging in major depressive disorder: evidence from a large scale fMRI analysis of Chinese participants},
  author={Yu Luo and Wen-Xiu Chen and Jiang Qiu and Tao Jia},
Major depressive disorder (MDD) is one of the most common mental health conditions that has been intensively investigated for its association with brain atrophy and mortality. Recent studies reveal that the deviation between the predicted and the chronological age can be a marker of accelerated brain aging to characterize MDD. However, current conclusions are usually drawn based on structural MRI information collected from Caucasian participants. The universality of this biomarker needs to be… 

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