Accelerated fat cell aging links oxidative stress and insulin resistance in adipocytes

  title={Accelerated fat cell aging links oxidative stress and insulin resistance in adipocytes},
  author={F. Monickaraj and S. Aravind and P. Nandhini and P. Prabu and C. Sathishkumar and V. Mohan and M. Balasubramanyam},
  journal={Journal of Biosciences},
  • F. Monickaraj, S. Aravind, +4 authors M. Balasubramanyam
  • Published 2012
  • Biology, Medicine
  • Journal of Biosciences
  • Telomere shortening is emerging as a biological indicator of accelerated aging and aging-related diseases including type 2 diabetes. While telomere length measurements were largely done in white blood cells, there is lack of studies on telomere length in relation to oxidative stress in target tissues affected in diabetes. Therefore, the aim of this study is to induct oxidative stress in adipocytes and to test whether these adipocytes exhibit shortened telomeres, senescence and functional… CONTINUE READING
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