Accelerated differentiation of osteoblast cells on polycaprolactone scaffolds driven by a combined effect of protein coating and plasma modification.

@article{Yildirim2010AcceleratedDO,
  title={Accelerated differentiation of osteoblast cells on polycaprolactone scaffolds driven by a combined effect of protein coating and plasma modification.},
  author={E. D. Yildirim and Robyn Besunder and Daphne D Pappas and Fred A Allen and Selçuk G{\"u}çeri and Wei Sun},
  journal={Biofabrication},
  year={2010},
  volume={2 1},
  pages={014109}
}
A combined effect of protein coating and plasma modification on the quality of the osteoblast-scaffold interaction was investigated. Three-dimensional polycaprolactone (PCL) scaffolds were manufactured by the precision extrusion deposition (PED) system. The structural, physical, chemical and biological cues were introduced to the surface through providing 3D structure, coating with adhesive protein fibronectin and modifying the surface with oxygen-based plasma. The changes in the surface… CONTINUE READING
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