Accelerated cutaneous nodulosis during infliximab therapy in a patient with rheumatoid arthritis.

@article{Mackley2004AcceleratedCN,
  title={Accelerated cutaneous nodulosis during infliximab therapy in a patient with rheumatoid arthritis.},
  author={Christine L. Mackley and Barbara E. Ostrov and Michael D. Ioffreda},
  journal={Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases},
  year={2004},
  volume={10 6},
  pages={
          336-8
        }
}
Up to one fourth of patients with rheumatoid arthritis (RA) may have extraarticular findings such as subcutaneous nodules. These are discrete subcutaneous granulomatous nodules located on extensor surfaces, especially of the elbows. Over the past 10 to 15 years, there have been reports of accelerated cutaneous nodulosis in patients receiving methotrexate therapy. Recently, antitumor necrosis factor alpha (anti-TNFalpha) biologic therapy has become commonplace in the management of RA, especially… CONTINUE READING
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