Accelerated corneal graft rejection in baby rats.

@article{Schwartzkopff2010AcceleratedCG,
  title={Accelerated corneal graft rejection in baby rats.},
  author={Johannes Schwartzkopff and Moritz C. Berger and Florian Birnbaum and Daniel B{\"o}hringer and Thomas Reinhard},
  journal={The British journal of ophthalmology},
  year={2010},
  volume={94 8},
  pages={
          1062-6
        }
}
BACKGROUND Penetrating keratoplasty in infants has a very poor outcome compared to adults. It is of intrinsic interest to gain insight into the still unknown immunological mechanisms of graft failure because any form of uncorrected corneal opacity leads to amblyopia. METHODS Allogeneic keratoplasty was performed between Lewis and Fisher rats. The recipients' ages were 10 and 3 weeks, respectively. All experiments were controlled syngeneically. Survival rates were calculated and cellular… CONTINUE READING
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