Acanthamoeba keratitis and contact lens wear

@article{Lindsay2007AcanthamoebaKA,
  title={Acanthamoeba keratitis and contact lens wear},
  author={Richard G Lindsay and Grant A. Watters and Richard Johnson and Susan E Ormonde and Grant R. Snibson},
  journal={Clinical and Experimental Optometry},
  year={2007},
  volume={90}
}
Acanthamoeba keratitis is a rare but serious complication of contact lens wear that may cause severe visual loss. The clinical picture is usually characterised by severe pain, sometimes disproportionate to the signs, with an early superficial keratitis that is often misdiagnosed as herpes simplex virus (HSV) keratitis. Advanced stages of the infection are usually characterised by central corneal epithelial loss and marked stromal opacification with subsequent loss of vision. In this paper, six… 
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Bilateral Acanthamoeba keratitis is an infectious complication of contact lens wear and with laboratory confirmation, vision often can be restored with medical therapy.
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More than two-thirds of the cases of Acanthamoeba keratitis related to contact lens use in a tertiary hospital in China were associated with orthokeratology, and the rate of therapeutic keratoplasty after 2005 was less than that before 2005.
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TLDR
The early definitive diagnosis of AK and the prompt initiation of appropriate therapy are essential for a favora ble clinical prognosis, hence, the importance of including Acanthamoeba in the differential diagnosis.
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Atypical AK can present as cruciate stromal infiltration and can be treated successfully with topical 0.02% chlorhexidine, and culture was positive for Acanthamoeba species.
Investigating Domestic Shower Settings as a Risk Factor for Acanthamoeba Keratitis
TLDR
The prevalence of Acanthamoeba species in domestic showers in the greater Sydney region, as well as the perception of water contamination of CL as being a risk factor for AK among previous AK patients and their family and friends are investigated.
Twenty Years of Acanthamoeba Keratitis
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The results suggested that patients with AK have persisted and increased over time at the ophthalmology center, and amoebic corneal infection can be considered as a new but well-established disease in Brazilian Ophthalmology and visual sciences.
Misdiagnosis of orthokeratology‐related Acanthamoeba keratitis as herpes simplex virus keratitis
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This work has shown that Werner’s syndrome has a unique association with spontaneous digital gangrene in infancy and decreased life span of cultured skin fibroblasts in infancy, and a homozygosity mapping of the Werner syndrome locus helps clarify these associations.
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