AcMNPV Core Gene ac109 Is Required for Budded Virion Transport to the Nucleus and for Occlusion of Viral Progeny

@inproceedings{Alfonso2012AcMNPVCG,
  title={AcMNPV Core Gene ac109 Is Required for Budded Virion Transport to the Nucleus and for Occlusion of Viral Progeny},
  author={Victoria Alfonso and Guillermo Andr{\'e}s Maroniche and Sol R. Reca and Mar{\'i}a Gabriela L{\'o}pez and Mariana Del Vas and Oscar Taboga},
  booktitle={PloS one},
  year={2012}
}
The Autographa californica multiple nucleopolyhedrovirus (AcMNPV) ac109 core gene has been previously characterized as an essential late gene. Our results showed that budded virions could be detected in supernatants of infected Sf-9 cells, even when ac109 knockout viruses displayed a single-cell infection phenotype. Moreover, confocal microscopy analysis revealed that budded virions can enter the cytoplasm but are unable to enter the cell nucleus. This defect could be repaired by complementing… CONTINUE READING

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Peng K , Wu M , Deng F , Song J , Dong C , et al . Identification of protein - protein interactions of the occlusion - derived virus - associated proteins of Helicoverpa armigera nucleopolyhedrovirus

GA Maroniche, VC Mongelli, V Alfonso, G Llauger, O Taboga
  • J Gen Virol
  • 2011