Abuse-related and abuse-limiting effects of methcathinone and the synthetic “bath salts” cathinone analogs methylenedioxypyrovalerone (MDPV), methylone and mephedrone on intracranial self-stimulation in rats

@article{Bonano2013AbuserelatedAA,
  title={Abuse-related and abuse-limiting effects of methcathinone and the synthetic “bath salts” cathinone analogs methylenedioxypyrovalerone (MDPV), methylone and mephedrone on intracranial self-stimulation in rats},
  author={Julie S Bonano and Richard A Glennon and Louis J. De Felice and Matthew L Banks and Stevens S. Negus},
  journal={Psychopharmacology},
  year={2013},
  volume={231},
  pages={199-207}
}
Abuse of synthetic cathinones, popularized as “bath salts,” has increased dramatically in the USA since their debut in 2010. Preclinical behavioral studies may clarify determinants of the abuse-related effects produced by these compounds. This study examined behavioral effects of (±)-methcathinone, (±)-3,4-methylenedioxypyrovalerone (MDPV), (±)-3,4-methylenedioxymethcathinone (methylone), and (±)-4-methylmethcathinone (mephedrone) in rats using intracranial self-stimulation (ICSS). Male Sprague… CONTINUE READING

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4-Methylmethcathinone (mephedrone): neuropharmacological effects of a designer stimulant of abuse.

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