Abuse potential of intranasal buprenorphine versus buprenorphine/naloxone in buprenorphine‐maintained heroin users

@article{Jones2015AbusePO,
  title={Abuse potential of intranasal buprenorphine versus buprenorphine/naloxone in buprenorphine‐maintained heroin users},
  author={J. Jones and M. Sullivan and S. Vosburg and J. Manubay and S. Mogali and Verena E Metz and S. Comer},
  journal={Addiction Biology},
  year={2015},
  volume={20}
}
  • J. Jones, M. Sullivan, +4 authors S. Comer
  • Published 2015
  • Medicine
  • Addiction Biology
  • In spite of the clinical utility of buprenorphine, parenteral abuse of this medication has been reported in several laboratory investigations and in the real world. Studies have demonstrated lower abuse liability of the buprenorphine/naloxone combination relative to buprenorphine alone. However, clinical research has not yet examined the utility of the combined formulation to deter intranasal use in a buprenorphine‐maintained population. Heroin‐using volunteers (n = 12) lived in the hospital… CONTINUE READING
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