Abuse of anabolic‐androgenic steroids and bodybuilding acne: an underestimated health problem

@article{Melnik2007AbuseOA,
  title={Abuse of anabolic‐androgenic steroids and bodybuilding acne: an underestimated health problem},
  author={Bodo C. Melnik and Thomas Jansen and Stephan Grabbe},
  journal={JDDG: Journal der Deutschen Dermatologischen Gesellschaft},
  year={2007},
  volume={5}
}
Abuse of anabolic‐androgenic steroids (AAS) by members of fitness centers and others in Germany has reached alarming dimensions. The health care system provides the illegal AAS to 48.1 % of abusers. Physicians are involved in illegal prescription of AAS and monitoring of 32.1 % of AAS abusers. Besides health‐threatening cardiovascular, hepatotoxic and psychiatric long‐term side effects of AAS, acne occurs in about 50 % of AAS abusers and is an important clinical indicator of AAS abuse… 

Cutaneous manifestations of anabolic–androgenic steroid use in athletes

Cutaneous manifestations develop early in the use of anabolic-androgenic steroids, placing dermatologists in a unique position to make an early diagnosis of AAS abuse in patients who engage in competitive sports.

Medical consequences of long-term anabolic-androgenic Steroids (AASs) abuses in athletes

The potential benefits of anabolic-androgenic steroids were not enough for consumers; therefore, identification and prevention of adverse effects on athletes taking these medications should be warned.

Testosterone and Anabolic Steroid Abuse

The management of patients presenting with infertility following AAS abuse entails substance discontinuation followed by medical therapy to regenerate the endocrine axis and stimulate testicular function.

Cardiovascular risk and androgenic anabolic steroids

The evidence for AAS having a negative effect on the cardiac and vascular tissue and the corresponding risk of developing cardiovascular disease is examined.

Androgen abuse in the community

  • B. Melnik
  • Medicine
    Current opinion in endocrinology, diabetes, and obesity
  • 2009
The use of androgens has changed from being a problem restricted to sports to one of public health concern and an increasing prevalence of androgen misuse in combination with other growth-promoting hormones and insulinotropic milk protein products has to be expected, which may have further promoting effects on the prevalence of chronic western diseases.

Consequences of the Use of Anabolic-Androgenic Steroids on Female Athletes’ Fertility

Evidence supports the abuse of steroids can adversely affect the fertility and reproductive organs of women severely and the use of AAS is a prohibited practice.

Exogenous Supraphysiological Doses of Anabolic-Androgenic Steroids:Controversial and Reciprocal Effects on Performance and Organs

There is no controlled study showing that testosterone derivatives significantly increase lean body mass or strength in people, so effectiveness of these drugs depend on many factors including doses, combinations of AAS, type of abuse, duration, types of training, individual differences, fitness level or training status.

Quantitative Influence of Exogenous Androgens on Serum Lipid Profile and Endocrine Functions

Results indicate that AAS have a more profound endocrine effect on the hypothalamic-pituitary-adrenal -axis than previously known and long term perturbation of endocrine parameters and cholesterol metabolism after discontinued abuse of anabolic androgenic steroids.

Histological Effect of Androgenic Anabolic Steroide Dianabol in Heart and Some Blood Parameters of Male Albino Rats

Examination of effect of androgenic anabolic steroid dianabol in heart and some blood parameters for male Albino rat showed that significant increase in RBC count, platelets total, Hb , p.c.v and ratio of lymphocytes in treatmssents groups compared with control, while the WBCs count show significant decrease.
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References

SHOWING 1-10 OF 116 REFERENCES

Testosterone and anabolic steroids and acne fulminans.

It was concluded that elevated blood levels of testosterone may play an important role in the pathogenesis of acne fulminans and the combined intake of testosterone and anabolic steroids by some sportsmen seems to be able to induce, or worsen, acne vulgaris.

Effects of anabolic-androgenic steroids on the pilosebaceous unit.

Examination of skin biopsy specimens from persons using anabolic-androgenic steroids demonstrates dramatic hypertrophy of the sebaceous glands. High dosages of testosterone and anabolic-androgenic

Linear keloids resulting from abuse of anabolic androgenic steroid drugs.

Anabolic androgenic steroid use by professional and amateur athletes is widespread. Dermatologic side effects are among the most frequent complications. Linear keloids are an unusual manifestation.

Effects of Androgenic-Anabolic Steroids in Athletes

Although AAS administration may affect erythropoiesis and blood haemoglobin concentrations, no effect on endurance performance was observed and little data about the effects of AAS on metabolic responses during exercise training and recovery are available and, therefore, do not allow firm conclusions.

Stanozolol as a novel therapeutic agent in dermatology.

Prevalence and risk factors for anabolic-androgenic steroid abuse in Australian high school students.

It is concluded that AAS abuse is relatively uncommon among Australian high school students but has distinctive and strong socio-economic and cultural predictors.

Anabolic-androgenic steroids as a gateway to opioid dependence.

Athletes who abuse anabolic–androgenic steroids may go on to abuse opioid agonist–antagonists such as nalbuphine1–3 or even classic opioids such as heroin, and this phenomenon among patients treated at Sunrise House was studied.

Anabolic-Androgenic Steroid Use Among 1,010 College Men.

Steroid users were not distinguishable from nonusers based on academic achievement or the use of other illicit drugs, cigarettes, or alcohol, but four used steroids primarily to improve personal appearance.

Effect of androgenic and anabolic steroids on the sebaceous gland in power athletes.

It was concluded that large doses of androgenic and anabolic steroids lead to an increase in sebum output in healthy young adult males.
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