Abuse of Recombinant Human Growth Hormone: Studies in Two Different Dog Models

@article{Rigamonti2004AbuseOR,
  title={Abuse of Recombinant Human Growth Hormone: Studies in Two Different Dog Models},
  author={Antonello Emilio Rigamonti and Diego Scanniffio and Sara M Bonomo and Silvano G. Cella and Alessandro Sartorio and Eugenio E. M{\"u}ller},
  journal={Neuroendocrinology},
  year={2004},
  volume={79},
  pages={237 - 246}
}
The search for inappropriately high growth hormone (GH) titers in plasma has been widely used to detect GH abuse, despite many shortcomings especially related to the pulsatile nature of GH secretion. Hence, the need for new anti-doping strategies. In the present study dogs were used to evaluate the ability of recombinant human GH (rhGH) to affect canine GH (cGH) release ensuing after somatostatin (SS) infusion withdrawal (SSIW) – a purported stimulus for the release of endogenous GH-releasing… 

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