Abuse-deterrent opioid formulations: Are they a pipe dream?

  title={Abuse-deterrent opioid formulations: Are they a pipe dream?},
  author={Nathaniel Katz},
  journal={Current Rheumatology Reports},
  • Nathaniel Katz
  • Published 2008
  • Medicine
  • Current Rheumatology Reports
  • The continued need for opioids to treat pain and their unavoidable link to abuse and addiction create a need for risk mitigation approaches that optimize their risk-benefit ratio. Abuse-deterrent formulations (ADFs) have emerged as a means for supporting opioid access while limiting abuse and its consequences. Several different types of ADFs have emerged including physical barriers to tampering, agonist-antagonist formulations, aversion, prodrugs, and alternative methods of administration. Each… CONTINUE READING
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