Abuse and dependence potential for the non-benzodiazepine hypnotics zolpidem and zopiclone: a review of case reports and epidemiological data.

@article{Hajak2003AbuseAD,
  title={Abuse and dependence potential for the non-benzodiazepine hypnotics zolpidem and zopiclone: a review of case reports and epidemiological data.},
  author={G{\"o}ran Hajak and Waiter E. M{\"u}ller and Hans-Ulrich Wittchen and David Pittrow and Wilhelm Kirch},
  journal={Addiction},
  year={2003},
  volume={98 10},
  pages={
          1371-8
        }
}
AIMS The non-benzodiazepine hypnotics zolpidem and zopiclone, which are indicated for short-term treatment of insomnia, were considered originally by physicians as almost devoid of abuse and dependence potential. Several recent publications, however, have suggested that both agents carry a significant risk of abuse. To substantiate and re-evaluate this situation, the world literature was reviewed for cases of dependence of both agents; these cases were analysed in order to identify certain… Expand
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