Abundant gene conversion between arms of palindromes in human and ape Y chromosomes

@article{Rozen2003AbundantGC,
  title={Abundant gene conversion between arms of palindromes in human and ape Y chromosomes},
  author={S. Rozen and H. Skaletsky and Janet D. Marszalek and P. Minx and Holland S. Cordum and R. Waterston and R. Wilson and D. Page},
  journal={Nature},
  year={2003},
  volume={423},
  pages={873-876}
}
Eight palindromes comprise one-quarter of the euchromatic DNA of the male-specific region of the human Y chromosome, the MSY. They contain many testis-specific genes and typically exhibit 99.97% intra-palindromic (arm-to-arm) sequence identity. This high degree of identity could be interpreted as evidence that the palindromes arose through duplication events that occurred about 100,000 years ago. Using comparative sequencing in great apes, we demonstrate here that at least six of these MSY… Expand
550 Citations

Paper Mentions

Large palindromes on the primate X Chromosome are preserved by natural selection
  • PDF
Birth, expansion, and death of VCY-containing palindromes on the human Y chromosome
  • 2
Y chromosome palindromes and gene conversion
  • 37
  • Highly Influenced
Y-Chromosome Structural Diversity in the Bonobo and Chimpanzee Lineages
  • 18
  • PDF
Extensive gene conversion drives the concerted evolution of paralogous copies of the SRY gene in European rabbits.
  • 25
  • Highly Influenced
  • PDF
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 55 REFERENCES
The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes
  • 1,866
  • PDF
Strong male-driven evolution of DNA sequences in humans and apes
  • 244
  • PDF
Recent Segmental Duplications in the Human Genome
  • 1,285
Gene conversion and natural selection in the evolution of X-linked color vision genes in higher primates.
  • Y. Zhou, W. Li
  • Biology, Medicine
  • Molecular biology and evolution
  • 1996
  • 43
  • PDF
Population genetic implications from sequence variation in four Y chromosome genes.
  • P. Shen, F. Wang, +10 authors P. Oefner
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 2000
  • 204
  • PDF
...
1
2
3
4
5
...