Abstract LB-219: Nuclear EGFR serves as a functional molecular target in triple-negative breast cancer.

@article{Brand2013AbstractLN,
  title={Abstract LB-219: Nuclear EGFR serves as a functional molecular target in triple-negative breast cancer.},
  author={T. Brand and M. Iida and Neha Luthar and Matthew J Wleklinski and Kellie T. Kostopoulos and D. L. Wheeler},
  journal={Cancer Research},
  year={2013},
  volume={73}
}
  • T. Brand, M. Iida, +3 authors D. L. Wheeler
  • Published 2013
  • Medicine
  • Cancer Research
  • Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC Triple negative breast cancer (TNBC) is a subclass of breast cancer (i.e. estrogen receptor negative, progesterone receptor negative, and HER-2 negative) that has poor prognosis and very few identified molecular targets. Strikingly the majority of TNBC's overexpress the epidermal growth factor receptor (EGFR), yet EGFR inhibition has had very little clinical benefit in this setting. This suggests a gap in our knowledge… CONTINUE READING