Abstract 986: High content analysis of 2D and 3D oncology models for target and phenotypic drug discovery

@article{Lachize2019Abstract9H,
  title={Abstract 986: High content analysis of 2D and 3D oncology models for target and phenotypic drug discovery},
  author={Servane Lachize and R. V. D. Bospoort and M. R. Silva and Niki van der Steentraten and Ian Gowers and R. Clark and J. Degroot and I. Waddell and Hajo Schiewe and S. Jain},
  journal={Cancer Research},
  year={2019},
  volume={79},
  pages={986-986}
}
  • Servane Lachize, R. V. D. Bospoort, +7 authors S. Jain
  • Published 2019
  • Biology
  • Cancer Research
  • Charles River (CR) has developed many disease-relevant cellular models to screen small molecules and genetic modifiers for target and phenotypic based drug discovery. Our expertise and portfolio in bespoke oncology model development (e.g. patient derived xenografts) covers a wide variety of target classes such as inhibitors of cell cycle, cellular motility and migration and transcription factor translocation. Complex cellular models derived from primary cells, patient derived embryonic stem… CONTINUE READING