Abstract 600: Liposomal C6 ceramide appears to potentiate enhanced chemotoxicity of pancreatic cancer.

@article{Wanebo2013Abstract6L,
  title={Abstract 600: Liposomal C6 ceramide appears to potentiate enhanced chemotoxicity of pancreatic cancer.},
  author={H. Wanebo and Cao Cong and L. Shu and D. Shrayer and Y. Wan and W. Bowen},
  journal={Cancer Research},
  year={2013},
  volume={73},
  pages={600-600}
}
  • H. Wanebo, Cao Cong, +3 authors W. Bowen
  • Published 2013
  • Medicine
  • Cancer Research
  • Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC Introduction: Pancreatic adenocarcinoma a highly lethal malignancy (5 yr survival ∼ 5%) is poorly responsive to all chemotherapy, in part related to presence of chemo resistant pathways: prosurvival (AKT/PI3K/mTOR and mutant KRAS. We previously demonstrated reversal of these resistant pathways by C6 Ceramide and now pursue optimum intracellular delivery using selected liposomal preparations of C6 Ceramide. Methods: C6… CONTINUE READING