Abstract 4931: ImmunoPET and fluorescence imaging with Zirconium-89 and IRDye 800CW labeled glycoengineered epidermal growth factor receptor antibody GA201

@article{Pool2014Abstract4I,
  title={Abstract 4931: ImmunoPET and fluorescence imaging with Zirconium-89 and IRDye 800CW labeled glycoengineered epidermal growth factor receptor antibody GA201},
  author={Martin Pool and Arjan Kol and Marjolijn N. Lub-de Hooge and Christian A. Gerdes and Steven A. De Jong and Elisabeth G. E. de Vries and Anton G. T. Terwisscha van Scheltinga},
  journal={Cancer Research},
  year={2014},
  volume={74},
  pages={4931-4931}
}
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Background: GA201 is a novel epidermal growth factor receptor (EGFR) monoclonal antibody (mAb), glycoengineered for enhanced antibody dependent cell-mediated cytotoxicity (ADCC). ADCC response is influenced by the amount of antibody bound to the membrane. Therefore we investigated specific accumulation and membrane binding of GA201 on tumor cells in vitro and in human cancer xenografts in vivo using Zirconium-89 (89Zr) and…