Abstract 4606: Novel mechanism for suppression of human colorectal cancer cell proliferation through induction of Wnt9A and suppression of β-catenin by resveratrol

@article{Ali2016Abstract4N,
  title={Abstract 4606: Novel mechanism for suppression of human colorectal cancer cell proliferation through induction of Wnt9A and suppression of β-catenin by resveratrol},
  author={I. Ali and B. Medegan and D. Braun},
  journal={Cancer Research},
  year={2016},
  volume={76},
  pages={4606-4606}
}
  • I. Ali, B. Medegan, D. Braun
  • Published 2016
  • Medicine
  • Cancer Research
  • Dysregulation of the Wnt pathway in histologically distinct cancers has been studied extensively. The canonical Wnt pathway (CWP) utilizing β-catenin is one of the major drivers for proliferation. In contrast, the capacity of the non-canonical Wnt pathway (NCWP) to regulate proliferation has not been studied extensively in neoplastic tissues. Our earlier studies demonstrated that RV-mediated suppression of colorectal cancer (CRC) cell proliferation correlated with upregulated expression of… CONTINUE READING