Abstract 4276: Oral contraceptive use and breast cancer risk: a cohort study ofBRCA1andBRCA2mutation carriers

@inproceedings{Schrijver2017Abstract4O,
  title={Abstract 4276: Oral contraceptive use and breast cancer risk: a cohort study ofBRCA1andBRCA2mutation carriers},
  author={Lieske H. Schrijver and Hakan L. Olsson and Antonis C. Antoniou and Roger L. Milne and Kelly M. Phillips and N. Andrieu and Michael R. Stratton and David E. Goldgar and Christoph Engel and Karin Kast and Marie-Jos{\'e} Blom and Thea M Mooij and John Llewielyn Hopper and F. E. van Leeuwen and Mary Beth Terry and Matti A. Rookus},
  year={2017}
}
Background: BRCA1 and BRCA2 mutation carriers are at high risk of breast and ovarian cancer. Oral contraceptive preparations (OCPs) may reduce ovarian cancer risk, but its effect on breast cancer risk remains unclear. Methods: Combined data from three cohorts of 5705 BRCA1 and 3521 BRCA2 mutation carriers (IBCCS, BCFR and kConFab) were analyzed using age-dependent Cox regression models stratified for study and birth cohort. We conducted the first prospective analyses on this topic. Our… CONTINUE READING

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