Abstract 4071: Sestrins modulate the expression of the metabolic stress sensor AMPK in breast cancer cells

@inproceedings{Sanli2011Abstract4S,
  title={Abstract 4071: Sestrins modulate the expression of the metabolic stress sensor AMPK in breast cancer cells},
  author={Toran Sanli and Katja D. Linher and Theodoros Tsakiridis and Gurmit Kaur Gurcharan Singh},
  year={2011}
}
Introduction: Sestrins (SESN) are stress response mediators that accumulate in cells exposed to genotoxic stresses, such as ultraviolet and ionizing radiation (IR). The three mammalian SESN (1-3) were recently shown to modulate signalling events. SESN1/2 are suggested to interact with and increasing the activity of the metabolic stress sensor AMP-activated protein kinase (AMPK). SESN1/2 have been postulated to act as scaffolding proteins that can bind targets of the AMPK metabolic pathway… CONTINUE READING

Similar Papers

Topics from this paper.