Abstract 3654: Recurrent deletions of 3q13.31 in human osteosarcoma commonly affect TUSC7 and LINC00901

@article{Ameline2019Abstract3R,
  title={Abstract 3654: Recurrent deletions of 3q13.31 in human osteosarcoma commonly affect TUSC7 and LINC00901},
  author={B. Ameline and M. Kovac and Karim H. Saba and M. Barenboim and M. Nathrath and K. Nord and D. Baumhoer},
  journal={Cancer Research},
  year={2019},
  volume={79},
  pages={3654-3654}
}
Background: Osteosarcoma, the most common primary tumor of bone, generally harbors complex structural rearrangements. In this study, we identified frequent mono- and bi-allelic deletions of the two long non-coding RNAs TUSC7 and LINC00901, both located on the long arm of chromosome 3 (3q13.31). Their precise biological function remain largely unknown, although it was suggested that TUSC7 may participate in micro-RNA trapping and thereby could be involved in tumor suppressor gene regulation… Expand