Abstract 2332: The new protein FAM110B regulates the expression of E-cadherin and is involved in cell migration and invasion

@article{Naouar2011Abstract2T,
  title={Abstract 2332: The new protein FAM110B regulates the expression of E-cadherin and is involved in cell migration and invasion},
  author={M. Naouar and D. Montaudon and Vincent Verbiest and A. Kauffmann and A. Laroche-Clary and C. Rey and F. Giorgi and P. Pourquier},
  journal={Cancer Research},
  year={2011},
  volume={71},
  pages={2332-2332}
}
FAM110B was first identified in a functional screen using genetic suppressor elements to identify new genes involved in the sensitivity to topoisomerase II poisons (Gros et al. Cancer Res, 2003 63: 164-71). FAM110B is extremely conserved in vertebrates. It shares strong sequence homologies with the two other members of this new family (FAM110A & C), but has no known functional domains. We generated a polyclonal antibody and showed that endogenous FAM110B had a MW of ≈40 kDa and was expressed in… Expand