Abstract 2300: MicroRNA-101 (miR-101) posttranscriptionally regulates the expression of EP4 receptor in colon cancers

@article{Onyeagucha2012Abstract2M,
  title={Abstract 2300: MicroRNA-101 (miR-101) posttranscriptionally regulates the expression of EP4 receptor in colon cancers},
  author={B. Onyeagucha and Anupama Chandramouli and M. E. Mercado-Pimentel and N. A. Shahin and B. LaFleur and R. Heimark and A. Bhattacharyya and M. Nelson},
  journal={Cancer Research},
  year={2012},
  volume={72},
  pages={2300-2300}
}
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL The predominant product of cyclooxygenase (COX-2) in the colon, prostaglandin (PG) E2 promotes carcinogenesis. Expression of the PGE2 receptor EP4 is upregulated during colorectal carcinogenesis. However the mechanism leading to deregulation of the EP4 receptor is not known. The present study was conducted to investigate the regulation of EP4 receptor by miRNAs. A bioinformatics search revealed a conserved target… Expand
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