Abstract 2261: DLGAP5, MAT1A, SKA3, and ZMYM5 are novel susceptibility genes for aggressive prostate cancer

@article{Lee2015Abstract2D,
  title={Abstract 2261: DLGAP5, MAT1A, SKA3, and ZMYM5 are novel susceptibility genes for aggressive prostate cancer},
  author={Minnkyong Lee and Kendra A. Williams and Y. Hu and J. Andreas and Shashank J. Patel and Suiyuan Zhang and N. Crawford},
  journal={Cancer Research},
  year={2015},
  volume={75},
  pages={2261-2261}
}
Prostate cancer is a common disease with approximately 233,000 men estimated to be diagnosed in the United States alone in 2014. Yet, it is usually an indolent disease with only 13% of patients succumbing to prostate cancer, and the molecular determinants of aggressive prostate cancer remain unclear. Previously, we reported that germline variation influences disease aggressiveness in the C57BL/6-Tg(TRAMP)8247Ng/J (TRAMP) mouse model. These mice develop neuroendocrine prostate tumors similar to… Expand
1 Citations
SKA3 Promotes tumor growth by regulating CDK2/P53 phosphorylation in hepatocellular carcinoma
  • Yuchen Hou, Ziming Wang, +8 authors Linwei Wu
  • Biology, Medicine
  • Cell Death & Disease
  • 2019
TLDR
The role of SKA3 is uncovered in regulating the apoptosis and proliferation of hepatocellular carcinoma cells and is found to affect tumor progression through the cell cycle and P53 signaling pathway. Expand