Abstract 1567: mTERT genetic vaccine chemotherapy combination augment antigen-specific immune response and confer tumor protection in time dependent fashion

@article{Ugel2012Abstract1M,
  title={Abstract 1567: mTERT genetic vaccine chemotherapy combination augment antigen-specific immune response and confer tumor protection in time dependent fashion},
  author={S. Ugel and John Facciaponte and E. Scarselli and C. Mennuni and N. L. Monica and G. Coukos and A. Facciabene},
  journal={Cancer Research},
  year={2012},
  volume={72},
  pages={1567-1567}
}
Successful cancer chemotherapy relies on the comprehensive elimination of tumor cells. However, at clinically tolerated doses, chemotherapeutic drugs usually fail to kill all tumor cells in vivo. Theoretically, to achieve complete eradication, partial tumor killing by chemotherapy should be accompanied by a “bystander effect” in which the immune system recognizes, attacks, and eradicates residual tumor cells. Doxorubicin) is an anthracycline antibiotic that intercalates with DNA, inhibiting its… Expand
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