Abstract 1489: Pri-let-7a-2 rs629367 associated with increased risk and poor survival of gastric cancer in Chinese by up-regulated let-7a expression
@article{Xu2014Abstract1P, title={Abstract 1489: Pri-let-7a-2 rs629367 associated with increased risk and poor survival of gastric cancer in Chinese by up-regulated let-7a expression}, author={Q. Xu and Y. Yuan}, journal={Cancer Research}, year={2014}, volume={74}, pages={1489-1489} }
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA
Abstract:Aim:Variant in pri-miRNA could affect miRNA expression and mature process or splicing efficiency, thus altering the hereditary susceptibility and prognosis of cancer. We aimed to assess miRNA-let-7 single nucleotide polymorphisms (SNP) associated with the risk and prognosis of gastric cancer (GC) as predicting biomarkers, and furthermore, its possible mechanisms. Method:We designed a two-stage case-control study to… CONTINUE READING