Abstract 1108: Ferritin binds breast cancer cells and tissue, and promotes proliferation independently of iron content

@inproceedings{Alkhateeb2011Abstract1F,
  title={Abstract 1108: Ferritin binds breast cancer cells and tissue, and promotes proliferation independently of iron content},
  author={Ahmed A. Alkhateeb and James R. Connor},
  year={2011}
}
Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL A connection between iron and breast tumorigenesis has been convincingly argued over the years. Several in vivo studies have demonstrated that iron-rich diets increase tumor incidence rate in carcinogen-induced mammary tumor models. Moreover, a large cohort study has recently associated mutations in the hemochromatosis (HFE) gene (promoting iron overload) with breast cancer risk in females. Individuals with mutations in… CONTINUE READING